Cancer-type | Pathway | Q-value | P-value | Pathway size | Cancer set size | DP | DN | GP | GN |
parson_gbm | hsa04510:Focal adhesion | 6.1e-16 | 4.36e-18 | 259 | 301 | 45 | 256 | 259 | 8681 |
parson_gbm | hsa04810:Regulation of actin cytoskeleton | 1.82e-09 | 2.6e-11 | 233 | 301 | 33 | 268 | 233 | 8707 |
parson_gbm | hsa05222:Small cell lung cancer | 2.87e-08 | 6.15e-10 | 117 | 301 | 22 | 279 | 117 | 8823 |
parson_gbm | hsa04012:ErbB signaling pathway | 6.1e-08 | 1.74e-09 | 190 | 301 | 27 | 274 | 190 | 8750 |
parson_gbm | hsa05215:Prostate cancer | 1.70e-07 | 7.02e-09 | 123 | 301 | 21 | 280 | 123 | 8817 |
parson_gbm | hsa05213:Endometrial cancer | 1.70e-07 | 7.27e-09 | 77 | 301 | 17 | 284 | 77 | 8863 |
parson_gbm | hsa04512:ECM-receptor interaction | 1.36e-06 | 6.78e-08 | 80 | 301 | 16 | 285 | 80 | 8860 |
parson_gbm | hsa05214:Glioma | 1.67e-06 | 9.53e-08 | 94 | 301 | 17 | 284 | 94 | 8846 |
parson_gbm | hsa04670:Leukocyte transendothelial migration | 5.71e-06 | 3.67e-07 | 131 | 301 | 19 | 282 | 131 | 8809 |
parson_gbm | hsa05218:Melanoma | 5.89e-06 | 4.21e-07 | 81 | 301 | 15 | 286 | 81 | 8859 |
parson_gbm | hsa05212:Pancreatic cancer | 8.49e-06 | 6.67e-07 | 123 | 301 | 18 | 283 | 123 | 8817 |
parson_gbm | hsa05210:Colorectal cancer | 2.39e-05 | 2.05e-06 | 120 | 301 | 17 | 284 | 120 | 8820 |
parson_gbm | hsa05223:Non-small cell lung cancer | 4.81e-05 | 4.47e-06 | 87 | 301 | 14 | 287 | 87 | 8853 |
parson_gbm | hsa04910:Insulin signaling pathway | 5.09e-05 | 5.09e-06 | 144 | 301 | 18 | 283 | 144 | 8796 |
parson_gbm | hsa05219:Bladder cancer | 5.12e-05 | 5.49e-06 | 64 | 301 | 12 | 289 | 64 | 8876 |
parson_gbm | hsa05220:Chronic myeloid leukemia | 5.53e-05 | 6.53e-06 | 132 | 301 | 17 | 284 | 132 | 8808 |
parson_gbm | hsa04020:Calcium signaling pathway | 5.53e-05 | 6.99e-06 | 163 | 301 | 19 | 282 | 163 | 8777 |
parson_gbm | hsa01430:Cell Communication | 5.53e-05 | 7.11e-06 | 91 | 301 | 14 | 287 | 91 | 8849 |
parson_gbm | hsa05221:Acute myeloid leukemia | 8.36e-05 | 1.14e-05 | 82 | 301 | 13 | 288 | 82 | 8858 |
parson_gbm | hsa04514:Cell adhesion molecules (CAMs) | 0.000144 | 2.06e-05 | 101 | 301 | 14 | 287 | 101 | 8839 |
parson_gbm | hsa04070:Phosphatidylinositol signaling system | 0.000246 | 3.69e-05 | 54 | 301 | 10 | 291 | 54 | 8886 |
parson_gbm | hsa04320:Dorso-ventral axis formation | 0.000292 | 4.59e-05 | 44 | 301 | 9 | 292 | 44 | 8896 |
parson_gbm | hsa04330:Notch signaling pathway | 0.000651 | 0.000110 | 50 | 301 | 9 | 292 | 50 | 8890 |
parson_gbm | hsa02010:ABC transporters - General | 0.000651 | 0.000119 | 19 | 301 | 6 | 295 | 19 | 8921 |
parson_gbm | hsa04530:Tight junction | 0.000651 | 0.000123 | 121 | 301 | 14 | 287 | 121 | 8819 |
parson_gbm | hsa04150:mTOR signaling pathway | 0.000651 | 0.000125 | 51 | 301 | 9 | 292 | 51 | 8889 |
parson_gbm | hsa05217:Basal cell carcinoma | 0.000651 | 0.000125 | 51 | 301 | 9 | 292 | 51 | 8889 |
parson_gbm | hsa00020:Citrate cycle (TCA cycle) | 0.000754 | 0.000151 | 20 | 301 | 6 | 295 | 20 | 8920 |
parson_gbm | hsa04730:Long-term depression | 0.00094 | 0.000195 | 96 | 301 | 12 | 289 | 96 | 8844 |
parson_gbm | hsa04520:Adherens junction | 0.00105 | 0.000225 | 113 | 301 | 13 | 288 | 113 | 8827 |
parson_gbm | hsa05211:Renal cell carcinoma | 0.00124 | 0.000275 | 100 | 301 | 12 | 289 | 100 | 8840 |
parson_gbm | hsa04662:B cell receptor signaling pathway | 0.00163 | 0.000378 | 74 | 301 | 10 | 291 | 74 | 8866 |
parson_gbm | hsa04360:Axon guidance | 0.00163 | 0.000384 | 120 | 301 | 13 | 288 | 120 | 8820 |
parson_gbm | hsa04370:VEGF signaling pathway | 0.00176 | 0.000426 | 90 | 301 | 11 | 290 | 90 | 8850 |
parson_gbm | hsa04620:Toll-like receptor signaling pathway | 0.00177 | 0.000444 | 122 | 301 | 13 | 288 | 122 | 8818 |
parson_gbm | hsa04610:Complement and coagulation cascades | 0.00178 | 0.000458 | 76 | 301 | 10 | 291 | 76 | 8864 |
parson_gbm | hsa04930:Type II diabetes mellitus | 0.00203 | 0.000536 | 50 | 301 | 8 | 293 | 50 | 8890 |
parson_gbm | hsa04080:Neuroactive ligand-receptor interaction | 0.0023 | 0.000624 | 216 | 301 | 18 | 283 | 216 | 8724 |
parson_gbm | hsa04010:MAPK signaling pathway | 0.00237 | 0.000659 | 275 | 301 | 21 | 280 | 275 | 8665 |
parson_gbm | hsa00650:Butanoate metabolism | 0.00258 | 0.000736 | 18 | 301 | 5 | 296 | 18 | 8922 |
parson_gbm | hsa00561:Glycerolipid metabolism | 0.00309 | 0.000905 | 19 | 301 | 5 | 296 | 19 | 8921 |
parson_gbm | hsa04210:Apoptosis | 0.00331 | 0.000994 | 117 | 301 | 12 | 289 | 117 | 8823 |
parson_gbm | hsa04540:Gap junction | 0.00387 | 0.00119 | 103 | 301 | 11 | 290 | 103 | 8837 |
parson_gbm | hsa04720:Long-term potentiation | 0.00409 | 0.00129 | 88 | 301 | 10 | 291 | 88 | 8852 |
parson_gbm | hsa00252:Alanine and aspartate metabolism | 0.00413 | 0.00133 | 21 | 301 | 5 | 296 | 21 | 8919 |
parson_gbm | hsa00620:Pyruvate metabolism | 0.00573 | 0.00188 | 23 | 301 | 5 | 296 | 23 | 8917 |
parson_gbm | hsa04630:Jak-STAT signaling pathway | 0.00806 | 0.00271 | 133 | 301 | 12 | 289 | 133 | 8807 |
parson_gbm | hsa00562:Inositol phosphate metabolism | 0.00824 | 0.00283 | 38 | 301 | 6 | 295 | 38 | 8902 |
parson_gbm | hsa04310:Wnt signaling pathway | 0.0148 | 0.00516 | 145 | 301 | 12 | 289 | 145 | 8795 |
parson_gbm | hsa04664:Fc epsilon RI signaling pathway | 0.0175 | 0.00639 | 112 | 301 | 10 | 291 | 112 | 8828 |
parson_gbm | hsa04660:T cell receptor signaling pathway | 0.0175 | 0.00639 | 112 | 301 | 10 | 291 | 112 | 8828 |
parson_gbm | hsa04650:Natural killer cell mediated cytotoxicity | 0.0207 | 0.00769 | 134 | 301 | 11 | 290 | 134 | 8806 |
parson_gbm | hsa04115:p53 signaling pathway | 0.0210 | 0.00811 | 64 | 301 | 7 | 294 | 64 | 8876 |
parson_gbm | hsa05030:Amyotrophic lateral sclerosis (ALS) | 0.0210 | 0.00813 | 21 | 301 | 4 | 297 | 21 | 8919 |
parson_gbm | hsa05216:Thyroid cancer | 0.0210 | 0.00824 | 34 | 301 | 5 | 296 | 34 | 8906 |
parson_gbm | hsa03030:DNA polymerase | 0.0234 | 0.00936 | 22 | 301 | 4 | 297 | 22 | 8918 |
parson_gbm | hsa00010:Glycolysis / Gluconeogenesis | 0.0367 | 0.0149 | 40 | 301 | 5 | 296 | 40 | 8900 |
parson_gbm | hsa03022:Basal transcription factors | 0.0374 | 0.0155 | 26 | 301 | 4 | 297 | 26 | 8914 |
parson_gbm | hsa00280:Valine, leucine and isoleucine degradation | 0.0393 | 0.0166 | 14 | 301 | 3 | 298 | 14 | 8926 |
parson_gbm | hsa01510:Neurodegenerative Diseases | 0.0438 | 0.0188 | 59 | 301 | 6 | 295 | 59 | 8881 |
parson_gbm | hsa01032:Glycan structures - degradation | 0.0439 | 0.0194 | 15 | 301 | 3 | 298 | 15 | 8925 |
parson_gbm | hsa00640:Propanoate metabolism | 0.0439 | 0.0194 | 15 | 301 | 3 | 298 | 15 | 8925 |
parson_gbm | hsa04614:Renin-angiotensin system | 0.05 | 0.0225 | 16 | 301 | 3 | 298 | 16 | 8924 |
parson_gbm | hsa05130:Pathogenic Escherichia coli infection - EHEC | 0.0524 | 0.0243 | 81 | 301 | 7 | 294 | 81 | 8859 |
parson_gbm | hsa05131:Pathogenic Escherichia coli infection - EPEC | 0.0524 | 0.0243 | 81 | 301 | 7 | 294 | 81 | 8859 |
parson_gbm | hsa04916:Melanogenesis | 0.0567 | 0.0269 | 102 | 301 | 8 | 293 | 102 | 8838 |
parson_gbm | hsa04350:TGF-beta signaling pathway | 0.0567 | 0.0271 | 122 | 301 | 9 | 292 | 122 | 8818 |
parson_gbm | hsa04060:Cytokine-cytokine receptor interaction | 0.0568 | 0.0276 | 229 | 301 | 14 | 287 | 229 | 8711 |
parson_gbm | hsa05010:Alzheimer's disease | 0.0636 | 0.0313 | 33 | 301 | 4 | 297 | 33 | 8907 |
parson_gbm | hsa05020:Parkinson's disease | 0.0657 | 0.0333 | 19 | 301 | 3 | 298 | 19 | 8921 |
parson_gbm | hsa00600:Sphingolipid metabolism | 0.0657 | 0.0333 | 19 | 301 | 3 | 298 | 19 | 8921 |
parson_gbm | hsa00564:Glycerophospholipid metabolism | 0.0664 | 0.0341 | 34 | 301 | 4 | 297 | 34 | 8906 |
parson_gbm | hsa04340:Hedgehog signaling pathway | 0.0672 | 0.035 | 51 | 301 | 5 | 296 | 51 | 8889 |
parson_gbm | hsa00230:Purine metabolism | 0.0696 | 0.0368 | 89 | 301 | 7 | 294 | 89 | 8851 |
parson_gbm | hsa00500:Starch and sucrose metabolism | 0.075 | 0.0402 | 36 | 301 | 4 | 297 | 36 | 8904 |
parson_gbm | hsa00251:Glutamate metabolism | 0.0854 | 0.0464 | 22 | 301 | 3 | 298 | 22 | 8918 |
parson_gbm | hsa00511:N-Glycan degradation | 0.0871 | 0.0479 | 9 | 301 | 2 | 299 | 9 | 8931 |
parson_gbm | hsa04742:Taste transduction | 0.0919 | 0.0512 | 23 | 301 | 3 | 298 | 23 | 8917 |
parson_gbm | hsa04120:Ubiquitin mediated proteolysis | 0.101 | 0.0574 | 120 | 301 | 8 | 293 | 120 | 8820 |
parson_gbm | hsa04110:Cell cycle | 0.101 | 0.058 | 164 | 301 | 10 | 291 | 164 | 8776 |
parson_gbm | hsa00410:beta-Alanine metabolism | 0.111 | 0.0651 | 11 | 301 | 2 | 299 | 11 | 8929 |
parson_gbm | hsa00903:Limonene and pinene degradation | 0.111 | 0.0651 | 11 | 301 | 2 | 299 | 11 | 8929 |
parson_gbm | hsa00590:Arachidonic acid metabolism | 0.133 | 0.0787 | 28 | 301 | 3 | 298 | 28 | 8912 |
parson_gbm | hsa00910:Nitrogen metabolism | 0.14 | 0.084 | 13 | 301 | 2 | 299 | 13 | 8927 |
parson_gbm | hsa00220:Urea cycle and metabolism of amino groups | 0.155 | 0.094 | 14 | 301 | 2 | 299 | 14 | 8926 |
parson_gbm | hsa04912:GnRH signaling pathway | 0.168 | 0.103 | 115 | 301 | 7 | 294 | 115 | 8825 |
parson_gbm | hsa04920:Adipocytokine signaling pathway | 0.17 | 0.106 | 72 | 301 | 5 | 296 | 72 | 8868 |
parson_gbm | hsa00240:Pyrimidine metabolism | 0.173 | 0.109 | 52 | 301 | 4 | 297 | 52 | 8888 |
parson_gbm | hsa00710:Carbon fixation | 0.181 | 0.115 | 16 | 301 | 2 | 299 | 16 | 8924 |
parson_gbm | hsa03320:PPAR signaling pathway | 0.191 | 0.126 | 35 | 301 | 3 | 298 | 35 | 8905 |
parson_gbm | hsa04140:Regulation of autophagy | 0.191 | 0.126 | 17 | 301 | 2 | 299 | 17 | 8923 |
parson_gbm | hsa00565:Ether lipid metabolism | 0.191 | 0.126 | 17 | 301 | 2 | 299 | 17 | 8923 |
parson_gbm | hsa05040:Huntington's disease | 0.199 | 0.133 | 36 | 301 | 3 | 298 | 36 | 8904 |
parson_gbm | hsa04640:Hematopoietic cell lineage | 0.199 | 0.133 | 78 | 301 | 5 | 296 | 78 | 8862 |
parson_gbm | hsa00071:Fatty acid metabolism | 0.202 | 0.137 | 18 | 301 | 2 | 299 | 18 | 8922 |
parson_gbm | hsa04740:Olfactory transduction | 0.216 | 0.148 | 19 | 301 | 2 | 299 | 19 | 8921 |
parson_gbm | hsa00260:Glycine, serine and threonine metabolism | 0.231 | 0.160 | 20 | 301 | 2 | 299 | 20 | 8920 |
parson_gbm | hsa00330:Arginine and proline metabolism | 0.279 | 0.195 | 23 | 301 | 2 | 299 | 23 | 8917 |
parson_gbm | hsa00790:Folate biosynthesis | 0.293 | 0.207 | 24 | 301 | 2 | 299 | 24 | 8916 |
parson_gbm | hsa00310:Lysine degradation | 0.307 | 0.219 | 25 | 301 | 2 | 299 | 25 | 8915 |
parson_gbm | hsa05120:Epithelial cell signaling in Helicobacter pylori infection | 0.325 | 0.235 | 72 | 301 | 4 | 297 | 72 | 8868 |
parson_gbm | hsa00380:Tryptophan metabolism | 0.384 | 0.28 | 30 | 301 | 2 | 299 | 30 | 8910 |
parson_gbm | hsa00120:Bile acid biosynthesis | 0.415 | 0.305 | 10 | 301 | 1 | 300 | 10 | 8930 |
parson_gbm | hsa00360:Phenylalanine metabolism | 0.429 | 0.328 | 11 | 301 | 1 | 300 | 11 | 8929 |
parson_gbm | hsa00591:Linoleic acid metabolism | 0.429 | 0.328 | 11 | 301 | 1 | 300 | 11 | 8929 |
parson_gbm | hsa00740:Riboflavin metabolism | 0.429 | 0.328 | 11 | 301 | 1 | 300 | 11 | 8929 |
parson_gbm | hsa00361:gamma-Hexachlorocyclohexane degradation | 0.429 | 0.328 | 11 | 301 | 1 | 300 | 11 | 8929 |
parson_gbm | hsa05060:Prion disease | 0.454 | 0.35 | 12 | 301 | 1 | 300 | 12 | 8928 |
parson_gbm | hsa00512:O-Glycan biosynthesis | 0.477 | 0.371 | 13 | 301 | 1 | 300 | 13 | 8927 |
parson_gbm | hsa01030:Glycan structures - biosynthesis 1 | 0.479 | 0.376 | 38 | 301 | 2 | 299 | 38 | 8902 |
parson_gbm | hsa04710:Circadian rhythm | 0.485 | 0.392 | 14 | 301 | 1 | 300 | 14 | 8926 |
parson_gbm | hsa03020:RNA polymerase | 0.485 | 0.392 | 14 | 301 | 1 | 300 | 14 | 8926 |
parson_gbm | hsa00150:Androgen and estrogen metabolism | 0.485 | 0.392 | 14 | 301 | 1 | 300 | 14 | 8926 |
parson_gbm | hsa00980:Metabolism of xenobiotics by cytochrome P450 | 0.505 | 0.412 | 15 | 301 | 1 | 300 | 15 | 8925 |
parson_gbm | hsa00340:Histidine metabolism | 0.52 | 0.431 | 16 | 301 | 1 | 300 | 16 | 8924 |
parson_gbm | hsa00480:Glutathione metabolism | 0.52 | 0.431 | 16 | 301 | 1 | 300 | 16 | 8924 |
parson_gbm | hsa00052:Galactose metabolism | 0.533 | 0.449 | 17 | 301 | 1 | 300 | 17 | 8923 |
parson_gbm | hsa00510:N-Glycan biosynthesis | 0.533 | 0.449 | 17 | 301 | 1 | 300 | 17 | 8923 |
parson_gbm | hsa01031:Glycan structures - biosynthesis 2 | 0.55 | 0.467 | 18 | 301 | 1 | 300 | 18 | 8922 |
parson_gbm | hsa03050:Proteasome | 0.622 | 0.534 | 22 | 301 | 1 | 300 | 22 | 8918 |
parson_gbm | hsa00350:Tyrosine metabolism | 0.635 | 0.549 | 23 | 301 | 1 | 300 | 23 | 8917 |
parson_gbm | hsa04940:Type I diabetes mellitus | 0.737 | 0.642 | 30 | 301 | 1 | 300 | 30 | 8910 |
parson_gbm | hsa04130:SNARE interactions in vesicular transport | 0.757 | 0.665 | 32 | 301 | 1 | 300 | 32 | 8908 |
parson_gbm | hsa03010:Ribosome | 0.849 | 0.752 | 41 | 301 | 1 | 300 | 41 | 8899 |
parson_gbm | hsa04612:Antigen processing and presentation | 0.972 | 0.868 | 60 | 301 | 1 | 300 | 60 | 8880 |
parson_gbm | hsa05050:Dentatorubropallidoluysian atrophy (DRPLA) | 1 | 1 | 18 | 301 | 0 | 301 | 18 | 8922 |
parson_gbm | hsa04950:Maturity onset diabetes of the young | 1 | 1 | 18 | 301 | 0 | 301 | 18 | 8922 |
parson_gbm | hsa00440:Aminophosphonate metabolism | 1 | 1 | 10 | 301 | 0 | 301 | 10 | 8930 |
parson_gbm | hsa00100:Biosynthesis of steroids | 1 | 1 | 11 | 301 | 0 | 301 | 11 | 8929 |
parson_gbm | hsa00860:Porphyrin and chlorophyll metabolism | 1 | 1 | 13 | 301 | 0 | 301 | 13 | 8927 |
parson_gbm | hsa05110:Cholera - Infection | 1 | 1 | 28 | 301 | 0 | 301 | 28 | 8912 |
parson_gbm | hsa00970:Aminoacyl-tRNA biosynthesis | 1 | 1 | 18 | 301 | 0 | 301 | 18 | 8922 |
parson_gbm | hsa00626:Naphthalene and anthracene degradation | 1 | 1 | 10 | 301 | 0 | 301 | 10 | 8930 |
parson_gbm | hsa00051:Fructose and mannose metabolism | 1 | 1 | 22 | 301 | 0 | 301 | 22 | 8918 |
parson_gbm | hsa00632:Benzoate degradation via CoA ligation | 1 | 1 | 9 | 301 | 0 | 301 | 9 | 8931 |
parson_gbm | hsa00030:Pentose phosphate pathway | 1 | 1 | 18 | 301 | 0 | 301 | 18 | 8922 |
parson_gbm | hsa00450:Selenoamino acid metabolism | 1 | 1 | 13 | 301 | 0 | 301 | 13 | 8927 |
parson_gbm | hsa00930:Caprolactam degradation | 1 | 1 | 10 | 301 | 0 | 301 | 10 | 8930 |
parson_gbm | hsa00530:Aminosugars metabolism | 1 | 1 | 13 | 301 | 0 | 301 | 13 | 8927 |
parson_gbm | hsa00190:Oxidative phosphorylation | 1 | 1 | 49 | 301 | 0 | 301 | 49 | 8891 |