Pathway Enlargement Enrichment results for BIOCARTA


Cancer-typePathwayQ-valueP-valuePathway sizeCancer set sizeDPDNGPGN
wood_colorectalh_tgfbPathway:TGF beta signaling pathway1.09e-055.58e-083381774338842
wood_colorectalh_ctcfPathway:CTCF: First Multivalent Nuclear Factor0.0003484.46e-062381576238852
wood_colorectalh_mTORPathway:mTOR Signaling Pathway0.0003485.35e-062481576248851
wood_colorectalh_intrinsicPathway:Intrinsic Prothrombin Activation Pathway0.001212.69e-051681477168859
wood_colorectalh_cxcr4Pathway:CXCR4 Signaling Pathway0.001213.1e-053681576368839
wood_colorectalh_nthiPathway:NFkB activation by Nontypeable Hemophilus influenzae0.001283.93e-053881576388837
wood_colorectalh_pitx2Pathway:Multi-step Regulation of Transcription by Pitx20.001435.75e-052081477208855
wood_colorectalh_alkPathway:ALK in cardiac myocytes0.001437.46e-054481576448831
wood_colorectalh_igf1mtorpathway:Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway0.001437.98e-052281477228853
wood_colorectalh_vegfPathway:VEGF, Hypoxia, and Angiogenesis0.001437.98e-052281477228853
wood_colorectalh_mapkPathway:MAPKinase Signaling Pathway0.001438.04e-05109817741098766
wood_colorectalh_nuclearRsPathway:Nuclear Receptors in Lipid Metabolism and Toxicity0.001519.3e-052381477238852
wood_colorectalh_nfatPathway:NFAT and Hypertrophy of the heart (Transcription in the broken heart)0.001640.0001094881576488827
wood_colorectalh_p53hypoxiaPathway:Hypoxia and p53 in the Cardiovascular system0.001980.0001422681477268849
wood_colorectalh_metPathway:Signaling of Hepatocyte Growth Factor Receptor0.001980.0001555281576528823
wood_colorectalh_il6Pathway:IL 6 signaling pathway0.001980.0001622781477278848
wood_colorectalh_gpcrPathway:Signaling Pathway from G-Protein Families0.002690.0002343081477308845
wood_colorectalh_eif4Pathway:Regulation of eIF4e and p70 S6 Kinase0.003080.0002943281477328843
wood_colorectalh_akapCentrosomePathway:Protein Kinase A at the Centrosome0.003083e-041281378128863
wood_colorectalh_g1Pathway:Cell Cycle: G1/S Check Point 0.003400.0003633481477348841
wood_colorectalh_HBxPathway:Calcium Signaling by HBx of Hepatitis B virus0.003400.0003671381378138862
wood_colorectalh_reckPathway:Inhibition of Matrix Metalloproteinases0.003760.0004421481378148861
wood_colorectalh_crebPathway:Transcription factor CREB and its extracellular signals0.003760.0004433681477368839
wood_colorectalh_no1Pathway:Actions of Nitric Oxide in the Heart0.005050.0006221681378168859
wood_colorectalh_fcer1Pathway:Fc Epsilon Receptor I Signaling in Mast Cells0.005920.000764281477428833
wood_colorectalh_her2Pathway:Role of ERBB2 in Signal Transduction and Oncology0.00670.0008934481477448831
wood_colorectalh_ptdinsPathway:Phosphoinositides and their downstream targets.0.0070.000971981378198856
wood_colorectalh_tcrPathway:T Cell Receptor Signaling Pathway0.00720.001044681477468829
wood_colorectalh_pmlPathway:Regulation of transcriptional activity by PML0.00720.001112081378208855
wood_colorectalh_ctla4Pathway:The Co-Stimulatory Signal During T-cell Activation0.00720.001112081378208855
wood_colorectalh_trkaPathway:Trka Receptor Signaling Pathway0.008930.001422281378228853
wood_colorectalh_mPRPathway:How Progesterone Initiates the Oocyte Maturation0.009720.001592381378238852
wood_colorectalh_igf1Pathway:IGF-1 Signaling Pathway0.01260.00222681378268849
wood_colorectalh_telPathway:Telomeres, Telomerase, Cellular Aging, and Immortality0.01260.00222681378268849
wood_colorectalh_integrinPathway:Integrin Signaling Pathway0.01300.002335881477588817
wood_colorectalh_wntPathway:WNT Signaling Pathway0.01310.002432781378278848
wood_colorectalh_insulinPathway:Insulin Signaling Pathway0.01370.002672881378288847
wood_colorectalh_gsk3Pathway:Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages0.01370.002672881378288847
wood_colorectalh_igf1rPathway:Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation0.01560.00323081378308845
wood_colorectalh_bArrestin-srcPathway:Roles of ?-arrestin-dependent Recruitment of Src Kinases in GPCR Signaling0.01560.00323081378308845
wood_colorectalh_CCR3Pathway:CCR3 signaling in Eosinophils0.01660.003493181378318844
wood_colorectalh_egfPathway:EGF Signaling Pathway0.01760.003793281378328843
wood_colorectalh_rasPathway:Ras Signaling Pathway0.01970.004443481378348841
wood_colorectalh_fMLPpathway:fMLP induced chemokine gene expression in HMC-1 cells0.01970.004443481378348841
wood_colorectalh_bcrPathway:BCR Signaling Pathway0.02230.005153681378368839
wood_colorectalh_extrinsicPathway:Extrinsic Prothrombin Activation Pathway0.02450.005911181279118864
wood_colorectalh_prionPathway:Prion Pathway0.02450.005911181279118864
wood_colorectalh_p38mapkPathway:p38 MAPK Signaling Pathway 0.02580.006353981378398836
wood_colorectalh_At1rPathway:Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling0.02640.006784081378408835
wood_colorectalh_erkPathway:Erk1/Erk2 Mapk Signaling pathway0.02640.006784081378408835
wood_colorectalh_RacCycDPathway:Influence of Ras and Rho proteins on G1 to S Transition0.02760.007234181378418834
wood_colorectalh_ctlPathway:CTL mediated immune response against target cells 0.03220.008931481279148861
wood_colorectalh_gcrPathway:Corticosteroids and cardioprotection0.03220.008931481279148861
wood_colorectalh_ghrelinPathway:Ghrelin: Regulation of Food Intake and Energy Homeostasis0.03220.008931481279148861
wood_colorectalh_il2rbPathway:IL-2 Receptor Beta Chain in T cell Activation0.03260.00924581378458830
wood_colorectalh_tob1Pathway:Role of Tob in T-cell activation0.03500.01011581279158860
wood_colorectalh_amiPathway:Acute Myocardial Infarction0.03780.01131681279168859
wood_colorectalh_longevityPathway:The IGF-1 Receptor and Longevity0.03780.01131681279168859
wood_colorectalh_nkcellsPathway:Ras-Independent pathway in NK cell-mediated cytotoxicity0.04570.01381881279188857
wood_colorectalh_CSKPathway:Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor0.04920.01521981279198856
wood_colorectalh_biopeptidesPathway:Bioactive Peptide Induced Signaling Pathway0.04920.01545581378558820
wood_colorectalh_etsPathway:METS affect on Macrophage Differentiation0.05140.01662081279208855
wood_colorectalh_mCalpainPathway:mCalpain and friends in Cell motility0.05140.01662081279208855
wood_colorectalh_il3Pathway:IL 3 signaling pathway0.05260.01812181279218854
wood_colorectalh_cdk5Pathway:Phosphorylation of MEK1 by cdk5/p35 down regulates the MAP kinase pathway0.05260.01812181279218854
wood_colorectalh_hSWI-SNFpathway:Chromatin Remodeling by hSWI/SNF ATP-dependent Complexes0.05260.01812181279218854
wood_colorectalh_cardiacegfPathway:Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy0.05260.01812181279218854
wood_colorectalh_ngfPathway:Nerve growth factor pathway (NGF)0.05620.01962281279228853
wood_colorectalh_keratinocytePathway:Keratinocyte Differentiation0.05650.026181378618814
wood_colorectalh_cdMacPathway:Cadmium induces DNA synthesis and proliferation in macrophages0.0590.02122381279238852
wood_colorectalh_spryPathway:Sprouty regulation of tyrosine kinase signals0.06180.02282481279248851
wood_colorectalh_epoPathway:EPO Signaling Pathway0.06180.02282481279248851
wood_colorectalh_erk5Pathway:Role of Erk5 in Neuronal Survival0.06820.02622681279268849
wood_colorectalh_gleevecpathway:Inhibition of Cellular Proliferation by Gleevec0.06820.02622681279268849
wood_colorectalh_TPOPathway:TPO Signaling Pathway0.06820.02622681279268849
wood_colorectalh_pdgfPathway:PDGF Signaling Pathway0.0710.0282781279278848
wood_colorectalh_sppaPathway:Aspirin Blocks Signaling Pathway Involved in Platelet Activation0.0710.0282781279278848
wood_colorectalh_ptenPathway:PTEN dependent cell cycle arrest and apoptosis0.07270.02982881279288847
wood_colorectalh_ecmPathway:Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia0.07270.02982881279288847
wood_colorectalh_carm-erPathway:CARM1 and Regulation of the Estrogen Receptor0.07270.02982881279288847
wood_colorectalh_il2Pathway:IL 2 signaling pathway0.07630.03172981279298846
wood_colorectalh_ghPathway:Growth Hormone Signaling Pathway0.08460.03563181279318844
wood_colorectalh_malPathway:Role of MAL in Rho-Mediated Activation of SRF0.0980.04173481279348841
wood_colorectalh_tffPathway:Trefoil Factors Initiate Mucosal Healing0.1070.04603681279368839
wood_colorectalh_pyk2Pathway:Links between Pyk2 and Map Kinases0.1540.06724581279458830
wood_colorectalh_mhcPathway:Antigen Processing and Presentation0.1590.070178118078868
wood_colorectalh_ranMSpathway:Role of Ran in mitotic spindle regulation0.1880.086998118098866
wood_colorectalh_shhPathway:Sonic Hedgehog (Shh) Pathway0.1880.086998118098866
wood_colorectalh_bbcellPathway:Bystander B Cell Activation0.1880.086998118098866
wood_colorectalh_eosinophilsPathway:The Role of Eosinophils in the Chemokine Network of Allergy0.1880.086998118098866
wood_colorectalh_btg2Pathway:BTG family proteins and cell cycle regulation0.2000.09521081180108865
wood_colorectalh_mef2dPathway:Role of MEF2D in T-cell Apoptosis0.2000.09521081180108865
wood_colorectalh_GATA3pathway:GATA3 participate in activating the Th2 cytokine genes expression0.2000.09521081180108865
wood_colorectalh_eif2Pathway:Regulation of eIF20.2020.1031181180118864
wood_colorectalh_calcineurinPathway:Effects of calcineurin in Keratinocyte Differentiation0.2020.1031181180118864
wood_colorectalh_bArrestinPathway:?-arrestins in GPCR Desensitization0.2020.1031181180118864
wood_colorectalh_stathminPathway:Stathmin and breast cancer resistance to antimicrotubule agents0.2020.1031181180118864
wood_colorectalh_eradPathway:ER?associated degradation (ERAD) Pathway0.2020.1031181180118864
wood_colorectalh_blymphocytePathway:B Lymphocyte Cell Surface Molecules0.2020.1031181180118864
wood_colorectalh_il5Pathway:IL 5 Signaling Pathway0.2020.1031181180118864
wood_colorectalh_cell2cellPathway:Cell to Cell Adhesion Signaling0.2070.1111281180128863
wood_colorectalh_rbPathway:RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage0.2070.1111281180128863
wood_colorectalh_setPathway:Granzyme A mediated Apoptosis Pathway0.2070.1111281180128863
wood_colorectalh_arfPathway:Tumor Suppressor Arf Inhibits Ribosomal Biogenesis0.2070.1111281180128863
wood_colorectalh_vipPathway:Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells0.2070.1111281180128863
wood_colorectalh_prc2Pathway:The PRC2 Complex Sets Long-term Gene Silencing Through Modification of Histone Tails0.2140.1201381180138862
wood_colorectalh_myosinPathway:PKC-catalyzed phosphorylation of inhibitory phosphoprotein of myosin phosphatase0.2140.1201381180138862
wood_colorectalh_tcraPathway:Lck and Fyn tyrosine kinases in initiation of TCR Activation0.2140.1201381180138862
wood_colorectalh_asbcellPathway:Antigen Dependent B Cell Activation0.2140.1201381180138862
wood_colorectalh_ucalpainPathway:uCalpain and friends in Cell spread0.220.1271481180148861
wood_colorectalh_d4gdiPathway:D4-GDI Signaling Pathway0.220.1271481180148861
wood_colorectalh_ranklPathway:Bone Remodelling0.220.1271481180148861
wood_colorectalh_ck1Pathway:Regulation of ck1/cdk5 by type 1 glutamate receptors0.220.1271481180148861
wood_colorectalh_skp2e2fPathway:E2F1 Destruction Pathway0.2260.1351581180158860
wood_colorectalh_achPathway:Role of nicotinic acetylcholine receptors in the regulation of apoptosis0.2260.1351581180158860
wood_colorectalh_hifPathway:Hypoxia-Inducible Factor in the Cardiovascular System0.2260.1351581180158860
wood_colorectalh_arapPathway:ADP-Ribosylation Factor0.2260.1351581180158860
wood_colorectalh_ps1Pathway:Presenilin action in Notch and Wnt signaling0.2350.1431681180168859
wood_colorectalh_smPathway:Spliceosomal Assembly0.2350.1431681180168859
wood_colorectalh_41bbPathway:The 4-1BB-dependent immune response0.2410.1511781180178858
wood_colorectalh_hdacPathway:Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK)0.2410.1511781180178858
wood_colorectalh_PDZsPathway:Synaptic Proteins at the Synaptic Junction0.2410.1511781180178858
wood_colorectalh_rarrxrPathway:Nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription in carcinoma cells0.2440.1591881180188857
wood_colorectalh_il7Pathway:IL-7 Signal Transduction0.2440.1591881180188857
wood_colorectalh_p53Pathway:p53 Signaling Pathway0.2440.1591881180188857
wood_colorectalh_tall1Pathway:TACI and BCMA stimulation of B cell immune responses.0.2440.1591881180188857
wood_colorectalh_Par1Pathway:Thrombin signaling and protease-activated receptors0.2440.1591881180188857
wood_colorectalh_barr-mapkPathway:Role of ?-arrestins in the activation and targeting of MAP kinases0.2510.1661981180198856
wood_colorectalh_tidPathway:Chaperones modulate interferon Signaling Pathway0.2510.1661981180198856
wood_colorectalh_atrbrcaPathway:Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility0.2610.1742081180208855
wood_colorectalh_il4Pathway:IL 4 signaling pathway0.2660.1812181180218854
wood_colorectalh_rhoPathway:Rho cell motility signaling pathway0.2660.1812181180218854
wood_colorectalh_th1th2Pathway:Th1/Th2 Differentiation0.2660.1812181180218854
wood_colorectalh_aktPathway:AKT Signaling Pathway0.2730.1892281180228853
wood_colorectalh_rac1Pathway:Rac 1 cell motility signaling pathway0.2730.1892281180228853
wood_colorectalh_dcPathway:Dendritic cells in regulating TH1 and TH2 Development0.2810.1962381180238852
wood_colorectalh_tnfr2Pathway:TNFR2 Signaling Pathway0.2870.2032481180248851
wood_colorectalh_g2Pathway:Cell Cycle: G2/M Checkpoint0.2870.2032481180248851
wood_colorectalh_inflamPathway:Cytokines and Inflammatory Response0.2960.2112581180258850
wood_colorectalh_RELAPathway:Acetylation and Deacetylation of RelA in The Nucleus0.3090.2252781180278848
wood_colorectalh_atmPathway:ATM Signaling Pathway0.3090.2252781180278848
wood_colorectalh_chemicalPathway:Apoptotic Signaling in Response to DNA Damage0.3090.2252781180278848
wood_colorectalh_vdrPathway:Control of Gene Expression by Vitamin D Receptor0.3140.2322881180288847
wood_colorectalh_edg1Pathway:Phospholipids as signalling intermediaries0.3140.2322881180288847
wood_colorectalh_caspasePathway:Caspase Cascade in Apoptosis0.3210.2392981180298846
wood_colorectalh_tollPathway:Toll-Like Receptor Pathway0.3640.2733481180348841
wood_colorectalh_agrPathway:Agrin in Postsynaptic Differentiation0.3880.2923781180378838
wood_colorectalh_pparaPathway:Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha)0.4270.3244281180428833
wood_colorectalh_HivnefPathway:HIV-I Nef: negative effector of Fas and TNF0.5920.4526581180658810
wood_colorectalh_p27Pathway:Regulation of p27 Phosphorylation during Cell Cycle Progression111781081178858
wood_colorectalh_ranbp2Pathway:Sumoylation by RanBP2 Regulates Transcriptional Repression111281081128863
wood_colorectalh_cblPathway:CBL mediated ligand-induced downregulation of EGF receptors111281081128863
wood_colorectalh_cellcyclePathway:Cyclins and Cell Cycle Regulation112681081268849
wood_colorectalh_cd40Pathway:CD40L Signaling Pathway111681081168859
wood_colorectalh_nfkbPathway:NF-kB Signaling Pathway112881081288847
wood_colorectalh_hcmvPathway:Human Cytomegalovirus and Map Kinase Pathways111781081178858
wood_colorectalh_mitochondriaPathway:Role of Mitochondria in Apoptotic Signaling112681081268849
wood_colorectalh_egfr_smrtePathway:Map Kinase Inactivation of SMRT Corepressor111081081108865
wood_colorectalh_deathPathway:Induction of apoptosis through DR3 and DR4/5 Death Receptors 113581081358840
wood_colorectalh_Ccr5Pathway:Pertussis toxin-insensitive CCR5 Signaling in Macrophage111281081128863
wood_colorectalh_fibrinolysisPathway:Fibrinolysis Pathway111481081148861
wood_colorectalh_thelperPathway:T Helper Cell Surface Molecules111281081128863
wood_colorectalh_ceramidePathway:Ceramide Signaling Pathway112881081288847
wood_colorectalh_fasPathway:FAS signaling pathway ( CD95 )113581081358840
wood_colorectalh_monocytePathway:Monocyte and its Surface Molecules111181081118864
wood_colorectalh_hsp27Pathway:Stress Induction of HSP Regulation111381081138862
wood_colorectalh_pgc1aPathway:Regulation of PGC-1a111181081118864
wood_colorectalh_eponfkbPathway:Erythropoietin mediated neuroprotection through NF-kB111481081148861
wood_colorectalh_stressPathway:TNF/Stress Related Signaling112681081268849
wood_colorectalh_rabPathway:Rab GTPases Mark Targets In The Endocytotic Machinery111581081158860
wood_colorectalh_tcytotoxicPathway:T Cytotoxic Cell Surface Molecules111481081148861
wood_colorectalh_mta3Pathway:Downregulated of MTA-3 in ER-negative Breast Tumors111081081108865
wood_colorectalh_Lis1Pathway:Lissencephaly gene (LIS1) in neuronal migration and development111181081118864
wood_colorectalh_badPathway:Regulation of BAD phosphorylation112281081228853
wood_colorectalh_bcellsurvivalPathway:B Cell Survival Pathway111381081138862
wood_colorectalh_tcapoptosisPathway:HIV Induced T Cell Apoptosis111081081108865
wood_colorectalh_tnfr1Pathway:TNFR1 Signaling Pathway113181081318844
wood_colorectalh_actinYPathway:Y branching of actin filaments111181081118864
wood_colorectalh_hesPathway:Segmentation Clock111381081138862
wood_colorectalh_il1rPathway:Signal transduction through IL1R112981081298846
wood_colorectalh_no2il12Pathway:NO2-dependent IL 12 Pathway in NK cells111181081118864
wood_colorectalh_lympathway:Adhesion and Diapedesis of Lymphocytes111281081128863
wood_colorectalh_akap95Pathway:AKAP95 role in mitosis and chromosome dynamics1198108198866
wood_colorectalh_LairPathway:Cells and Molecules involved in local acute inflammatory response111381081138862
wood_colorectalh_granulocytesPathway:Adhesion and Diapedesis of Granulocytes111381081138862
wood_colorectalh_compPathway:Complement Pathway111381081138862
wood_colorectalh_arenrf2Pathway:Oxidative Stress Induced Gene Expression Via Nrf2111881081188857
wood_colorectalh_nktPathway:Selective expression of chemokine receptors during T-cell polarization112781081278848
wood_colorectalh_il17Pathway:IL 17 Signaling Pathway111681081168859
wood_colorectalh_IL12Pathway:IL12 and Stat4 Dependent Signaling Pathway in Th1 Development112181081218854
wood_colorectalh_glycolysisPathway:Glycolysis Pathway111081081108865
wood_colorectalh_stemPathway:Regulation of hematopoiesis by cytokines111481081148861
wood_colorectalh_erythPathway:Erythrocyte Differentiation Pathway111381081138862
wood_colorectalh_cytokinePathway:Cytokine Network111981081198856
wood_colorectalh_eicosanoidPathway:Eicosanoid Metabolism111281081128863